BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Lcn2em5Cd5686/Gpt |
| Strain Number: | T014584 |
| Official Symbol: | Lcn2 |
| Strain Strategy: | T014584. Lcn2 Cas9-KO Strategy-EN.pdf |
| Official Full Name: | lipocalin 2 |
| Also Known As: | 24p3,AW212229,NRL,Sip24 |
| NCBI Number: | 16819 |
| MGI Number: | 96757 |
| Chromosome: | 2 |
| Deletion (size): | -5686bp |
| Research Areas: | Metabolic research,adipose tissue,homeostasis/metabolism,Developmental Biology,growth/size/body,mortality/aging,immune system,Physiological system,cardiovascular system,reproductive system,digestive/alimentary system,liver/biliary system,renal/urinary system,endocrine/exocrine glands,hematopoietic system,Cell biology,Cell death,cellular,Cell localization,Cytoplasmic vesicle,Molecular biology,Signal Transduction |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Knockout (KO) |
| Genotyping Protocols: | T014584.Lcn2 Genotyping Protocol(KO).pdf |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Lipocalin-2 in neutrophils induces ferroptosis in septic cardiac dysfunction via increasing labile iron pool of cardiomyocytes. Front Cardiovasc Med (2022)2. Lipocalin-2 promotes CKD vascular calcification by aggravating VSMCs ferroptosis through NCOA4/FTH1-mediated ferritinophagy. Cell Death Dis (2024) |
| Gene Family: | Lipocalins |