C57BL/6JGpt-Mlklem1Cflox/Gpt
Mlkl-flox|Strain NO.T052126
Conditional knockout (cKO)
- Product Type:
- Quantity: - +
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- Age:
- Genotype:
BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Mlklem1Cflox/Gpt |
| Strain Number: | T052126 |
| Official Symbol: | Mlkl |
| Strain Strategy: | Log in to read more |
| Official Full Name: | mixed lineage kinase domain-like |
| Also Known As: | 9130019I15Rik |
| NCBI Number: | 74568 |
| MGI Number: | 1921818 |
| Chromosome: | 8 |
| Distance Between Two Loxps: | 11976bp |
| Research Areas: | Metabolic research,Protein metabolism,homeostasis/metabolism,immune system,Physiological system,hematopoietic system,Cell biology,Cell death,cellular,Organelles membrane,Molecular biology,Signal Transduction |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Conditional knockout (cKO) |
| Genotyping Protocols: | Log in to read more |
| Inventory Status: | Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Necroptosis-mediated HMGB1 secretion of keratinocytes as a key step for inflammation development in contact hypersensitivity2. Inflammatory adhesion mediates myocardial segmental necroptosis induced by mixed lineage kinase domain-like protein in acute myocardial infarction3. ZBP1-mediated PANoptosis is a crucial lethal form in diverse keratinocyte death modalities in UVB-induced skin injury |