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C57BL/6JGpt-H11em1Cin(Syn1-iCre)/Gpt

H11-Syn1-iCre|Strain NO.T052699

Knockin (KI)

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BASIC INFORMATION
Strain Name: C57BL/6JGpt-H11em1Cin(Syn1-iCre)/Gpt
Strain Number: T052699
Official Symbol: Syn1,iCre
Strain Strategy: T052699.H11-Syn1-iCre-polyA Strategy-EN.pdf
Official Full Name: synapsin I
Also Known As: Syn-1,Syn1-S
NCBI Number: 20964
MGI Number: 98460
Chromosome: 11
Research Areas: Tool Mice,Cre/Dre
Strain Background: [N000013] C57BL/6JGpt
Modification Type: Knockin (KI)
Genotyping Protocols: T052699.H11-Syn1-iCre Genotyping Protocol(KI) .pdf
Inventory Status: Live,Cryopreserved
Sale Status: IF (Available for Distribution)
Health Status: Specific pathogen free (SPF)
Health Report: Please log in to view
Publications: 1. Differential roles of NMDAR subunits 2A and 2B in mediating peripheral and central sensitization contributing to orofacial neuropathic pain. Brain Behav Immun (2022)2. Targeting the postsynaptic scaffolding protein PSD-95 enhances BDNF signaling to mitigate depression-like behaviors in mice. Sci Signal (2024)3. TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4. International journal of biological sciences (2025)4. Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4. Cell death and differentiation (2025)
Gene Family: Synapsins