Drug Resistance

Autoimmune Disease Models
Autoimmune Nephropathy ModelsAsthma ModelsSystemic Lupus Erythematosus (SLE) ModelsSjögren's Syndrome ModelsAutoimmune Dermatoses Models Neuroimmune Disease ModelsInflammatory Bowel Disease ModelsRheumatoid Arthritis ModelsImmune Reconstitution Autoimmune Disease Models
Metabolic Disease Mouse Models
Obesity ModelsDiabetes ModelsMASH ModelsOsteoporosis ModelsHyperuricemia Models
Wild Mouse 750
Wild Mouse 750
Rare Disease Mouse Models
Autosomal Dominant Polycystic Kidney Disease (ADPKD)Progressive Muscular Dystrophy ModelsHemophilia A Models
Neurological Disease Mouse Models
Alzheimer's Disease (AD) ModelsHumanized Alzheimer's Disease (AD) ModelsParkinson's Disease (PD) ModelsHuntington's Disease (HD) ModelsAmyotrophic Lateral Sclerosis (ALS) ModelsTransthyretin Amyloidosis (ATTR) ModelsPain Mouse ModelsDuchenne Muscular Dystrophy (DMD) Models
Oncology Mouse Models
Human Xenograft ModelsDrug ResistanceT-Cell EngagersHumanized Immune Checkpoint ModelsHumanized Immune System ModelsSpontaneous Tumor Models
Cardiovascular Disease Mouse Models
Heart Failure ModelsHypertension ModelsAtherosclerosis ModelsAdvanced Cardiovascular and Metabolic Complication ModelsHyperlipidemia ModelsHypertropic Cardiomyopathy ModelsStroke ModelsThrombosis Models
Humanized Immune System Models
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Organs or Tissue Humanized Mouse Models
Wild Mouse 765
Wild Mouse 765

Drug resistance remains one of the greatest challenges in oncology, often leading to treatment failure and cancer relapse. Tumors can develop resistance through a myriad of methods: genetic mutations, pathway reactivation, or adaptation within the tumor microenvironment. To understand the mechanisms behind drug resistance and evaluate new treatment strategies require advanced preclinical models that accurately reflect drug resistance patterns.


GemPharmatech offers a wide range of genetically engineered mouse models and custom tumor resistance models that enable researchers to study primary and acquired resistance across various cancer types. GemPharmatech also offers preclinical services such as with in vivo efficacy, combination therapy testing, and tissue analysis to support you on your journey to uncover, overcome or prevent drug resistance.


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Need help with your drug resistance study? Contact us and let our team of experts help you.